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Site-Specific Identification of Non-β-Strand Conformations in Alzheimer's β-Amyloid Fibrils by Solid-State NMR

The most well-established structural feature of amyloid fibrils is the cross-β motif, an extended β-sheet structure formed by β-strands oriented perpendicular to the long fibril axis. Direct experimental identification of non-β-strand conformations in amyloid fibrils has not been reported previously...

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Main Authors: Antzutkin, Oleg N., Balbach, John J., Tycko, Robert
Formato: Artigo
Idioma:Inglês
Publicado: Biophysical Society 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302893/
https://ncbi.nlm.nih.gov/pubmed/12719262
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