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BeKm-1 Is a HERG-Specific Toxin that Shares the Structure with ChTx but the Mechanism of Action with ErgTx1

Peptide toxins with disulfide-stabilized structures have been used as molecular calipers to probe the outer vestibule structure of K channels. We want to apply this approach to the human ether-a-go-go-related gene (HERG) channel, whose outer vestibule is unique in structure and function among voltag...

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Hlavní autoři: Zhang, Mei, Korolkova, Yuliya V., Liu, Jie, Jiang, Min, Grishin, Eugene V., Tseng, Gea-Ny
Médium: Artigo
Jazyk:Inglês
Vydáno: Biophysical Society 2003
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302864/
https://ncbi.nlm.nih.gov/pubmed/12719233
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