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Sedimentation Velocity Analysis of Flexible Macromolecules: Self-Association and Tangling of Amyloid Fibrils

A novel bead modeling technique has been developed for the analysis of the sedimentation velocity behavior of flexible fibrils. The method involves the generation of a family of bead models representing a sample of the conformations available to the molecule and the calculation of the sedimentation...

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Detalhes bibliográficos
Main Authors: MacRaild, Christopher A., Hatters, Danny M., Lawrence, Lynne J., Howlett, Geoffrey J.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302822/
https://ncbi.nlm.nih.gov/pubmed/12668464
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