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Mechanism of Accelerated Assembly of β-Amyloid Filaments into Fibrils by KLVFFK(6)
Extracellular senile plaques are a central pathological feature of Alzheimer's disease. At the core of these plaques are fibrillar deposits of β-amyloid peptide (Aβ). In vitro, Aβ spontaneously assembles into amyloid fibrils of cross-β sheet structure. Although it was once believed that the fib...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Biophysical Society
2004
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1304184/ https://ncbi.nlm.nih.gov/pubmed/15111432 |
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