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Structural Modeling Extends QSAR Analysis of Antibody-Lysozyme Interactions to 3D-QSAR

This work shows that quantitative multivariate modeling is an emerging possibility for unraveling protein-protein interactions using a combination of designed mutations with sequence and structure information. Using this approach, it is possible to stereochemically determine which residue properties...

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Auteurs principaux: Freyhult, Eva K., Andersson, Karl, Gustafsson, Mats G.
Format: Artigo
Langue:Inglês
Publié: Biophysical Society 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302793/
https://ncbi.nlm.nih.gov/pubmed/12668435
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