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Thermodynamic Characterization of the Folding Coupled DNA Binding by the Monomeric Transcription Activator GCN4 Peptide

Dimerization is a widely believed critical requirement for the yeast transcriptional activator GCN4 specifically recognizing its DNA target sites. Nonetheless, the binding of the monomeric GCN4 to DNA target sites AP-1 and ATF/CREB was recently detected by kinetic studies. Here, for the first time,...

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Autors principals: Wang, Xu, Cao, Wei, Cao, Aoneng, Lai, Luhua
Format: Artigo
Idioma:Inglês
Publicat: Biophysical Society 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302755/
https://ncbi.nlm.nih.gov/pubmed/12609888
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