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A Minimal Physically Realistic Protein-Like Lattice Model: Designing an Energy Landscape that Ensures All-Or-None Folding to a Unique Native State

A simple protein model restricted to the face-centered cubic lattice has been studied. The model interaction scheme includes attractive interactions between hydrophobic (H) residues, repulsive interactions between hydrophobic and polar (P) residues, and orientation-dependent P-P interactions. Additi...

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Detalhes bibliográficos
Main Authors: Pokarowski, Piotr, Kolinski, Andrzej, Skolnick, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302725/
https://ncbi.nlm.nih.gov/pubmed/12609858
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