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Conformational partitioning of the fusion peptide of HIV-1 gp41 and its structural analogs in bilayer membranes.

Experiments have shown that the ability of the HIV-1 virus to infect cells can be greatly diminished by deactivation of the N-terminal (fusion) peptide of its glycoprotein gp41. Deactivation can be achieved by the deletion of several amino acid residues, or replacement of a hydrophobic residue with...

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Bibliographic Details
Main Authors: Maddox, Michael W, Longo, Marjorie L
Format: Artigo
Language:Inglês
Published: 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302388/
https://ncbi.nlm.nih.gov/pubmed/12496080
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