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Fully hydrophobic HIV gp41 adopts a hemifusion-like conformation in phospholipid bilayers

The HIV envelope glycoprotein mediates virus entry into target cells by fusing the virus lipid envelope with the cell membrane. This process requires large-scale conformational changes of the fusion protein gp41. Current understanding of the mechanisms with which gp41 induces membrane merger is limi...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Lee, Myungwoon, Morgan, Chloe A., Hong, Mei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779440/
https://ncbi.nlm.nih.gov/pubmed/31409642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009542
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