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An automated two-dimensional optical force clamp for single molecule studies.

We constructed a next-generation optical trapping instrument to study the motility of single motor proteins, such as kinesin moving along a microtubule. The instrument can be operated as a two-dimensional force clamp, applying loads of fixed magnitude and direction to motor-coated microscopic beads...

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Detalhes bibliográficos
Main Authors: Lang, Matthew J, Asbury, Charles L, Shaevitz, Joshua W, Block, Steven M
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302163/
https://ncbi.nlm.nih.gov/pubmed/12080136
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