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Reduced transition between open and inactivated channel states underlies 5HT increased I(Na+) in rat nociceptors.

We previously demonstrated that activation of a 5HT(4) receptor coupled cAMP-dependent signaling pathway increases tetrodotoxin-resistant Na(+) current (I(Na)) in a nociceptor-like subpopulation of rat dorsal root ganglion cells (type 2). In the present study we used electrophysiology experiments an...

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Autors principals: d'Alcantara, Pablo, Cardenas, Luz M, Swillens, Stéphane, Scroggs, Reese S
Format: Artigo
Idioma:Inglês
Publicat: 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302124/
https://ncbi.nlm.nih.gov/pubmed/12080097
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