Ca2+ activation of RyR1 is not necessary for the initiation of skeletal-type excitation-contraction coupling.

Although an elevation in myoplasmic Ca2+ can activate the skeletal muscle ryanodine receptor (RyR1), the function of this Ca2+ activation is unclear because extracellular Ca2+ influx is unnecessary for skeletal-type EC coupling. To determine whether Ca2+ activation of RyR1 is necessary for the initi...

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Hauptverfasser: O'Brien, Jennifer J, Feng, Wei, Allen, Paul D, Chen, S R Wayne, Pessah, Isaac N, Beam, Kurt G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2002
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302033/
https://ncbi.nlm.nih.gov/pubmed/11964231
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