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Subunit-selective contribution to channel gating of the M4 domain of the nicotinic receptor.

The muscle nicotinic receptor (AChR) is a pentamer of four different subunits, each of which contains four transmembrane domains (M1-M4). We recently showed that channel opening and closing rates of the AChR depend on a hydrogen bond involving a threonine at position 14' of the M4 domain in the...

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Bibliographische Detailangaben
Hauptverfasser: Bouzat, Cecilia, Gumilar, Fernanda, del Carmen Esandi, María, Sine, Steven M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301988/
https://ncbi.nlm.nih.gov/pubmed/11916850
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