Sustained overexpression of IGF-1 prevents age-dependent decrease in charge movement and intracellular Ca(2+) in mouse skeletal muscle.

In this work we tested the hypothesis that transgenic sustained overexpression of IGF-1 prevents age-dependent decreases in charge movement and intracellular Ca(2+) in skeletal muscle fibers. To this end, short flexor digitorum brevis (FDB) muscle fibers from 5-7- and 21-24-month-old FVB (wild-type)...

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Bibliographic Details
Main Authors: Wang, Zhong-Min, Messi, María Laura, Delbono, Osvaldo
Format: Artigo
Language:Inglês
Published: 2002
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301936/
https://ncbi.nlm.nih.gov/pubmed/11867450
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