Imperatoxin a enhances Ca(2+) release in developing skeletal muscle containing ryanodine receptor type 3.

Most adult mammalian skeletal muscles contain only one isoform of ryanodine receptor (RyR1), whereas neonatal muscles contain two isoforms (RyR1 and RyR3). Membrane depolarization fails to evoke calcium release in muscle cells lacking RyR1, demonstrating an essential role for this isoform in excitat...

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Autores principales: Nabhani, Thomas, Zhu, Xinsheng, Simeoni, Ilenia, Sorrentino, Vincenzo, Valdivia, Héctor H, García, Jesús
Formato: Artigo
Lenguaje:Inglês
Publicado: 2002
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301934/
https://ncbi.nlm.nih.gov/pubmed/11867448
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