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Aggregation and retention of human urokinase type plasminogen activator in the yeast endoplasmic reticulum
BACKGROUND: Secretion of recombinant proteins in yeast can be affected by their improper folding in the endoplasmic reticulum and subsequent elimination of the misfolded molecules via the endoplasmic reticulum associated protein degradation pathway. Recombinant proteins can also be degraded by the v...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC130179/ https://ncbi.nlm.nih.gov/pubmed/12366865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-3-15 |
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