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A semiflexible polymer model applied to loop formation in DNA hairpins.

A statistical mechanical "zipper" model is applied to describe the equilibrium melting of short DNA hairpins with poly(dT) loops ranging from 4 to 12 bases in the loop. The free energy of loop formation is expressed in terms of the persistence length of the chain. This method provides a ne...

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Autores principales: Kuznetsov, S V, Shen, Y, Benight, A S, Ansari, A
Formato: Artigo
Lenguaje:Inglês
Publicado: 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301751/
https://ncbi.nlm.nih.gov/pubmed/11606297
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