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Spin and fluorescent probing of the binding interface between tissue factor and factor VIIa at multiple sites.

The specific complex between the extracellular part of tissue factor (sTF) and factor VIIa (FVIIa) was chosen as a model for studies of the binding interface between two interacting proteins. Six surface-exposed positions in sTF, residues known to contribute to the sTF-FVIIa interaction, were select...

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Detalhes bibliográficos
Main Authors: Owenius, R, Osterlund, M, Svensson, M, Lindgren, M, Persson, E, Freskgård, P O, Carlsson, U
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301706/
https://ncbi.nlm.nih.gov/pubmed/11566805
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