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Calculations of free-energy contributions to protein-RNA complex stabilization.
The problem of calculating binding affinities of protein-RNA complexes is addressed by analyzing a computational strategy of modeling electrostatic free energies based on a nonlinear Poisson-Boltzmann (NLPB) model and linear response approximation (LRA). The underlying idea is to treat binding as a...
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Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
2001
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Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1301660/ https://ncbi.nlm.nih.gov/pubmed/11566759 |
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