Calculations of free-energy contributions to protein-RNA complex stabilization.

The problem of calculating binding affinities of protein-RNA complexes is addressed by analyzing a computational strategy of modeling electrostatic free energies based on a nonlinear Poisson-Boltzmann (NLPB) model and linear response approximation (LRA). The underlying idea is to treat binding as a...

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Bibliographic Details
Main Author: Olson, M A
Format: Artigo
Language:Inglês
Published: 2001
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301660/
https://ncbi.nlm.nih.gov/pubmed/11566759
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