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Distinct roles for two RAD51-related genes in Trypanosoma brucei antigenic variation

In Trypanosoma brucei, DNA recombination is crucial in antigenic variation, a strategy for evading the mammalian host immune system found in a wide variety of pathogens. T.brucei has the capacity to encode >1000 antigenically distinct variant surface glycoproteins (VSGs). By ensuring that only on...

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Hlavní autoři: Proudfoot, Chris, McCulloch, Richard
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301600/
https://ncbi.nlm.nih.gov/pubmed/16326865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki996
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