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Distinct roles for two RAD51-related genes in Trypanosoma brucei antigenic variation
In Trypanosoma brucei, DNA recombination is crucial in antigenic variation, a strategy for evading the mammalian host immune system found in a wide variety of pathogens. T.brucei has the capacity to encode >1000 antigenically distinct variant surface glycoproteins (VSGs). By ensuring that only on...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1301600/ https://ncbi.nlm.nih.gov/pubmed/16326865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki996 |
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