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CTCF binds the proximal exonic region of hTERT and inhibits its transcription

The expression of the catalytic subunit (hTERT) represents the limiting factor for telomerase activity. Previously, we detected a transcriptional repressor effect of the proximal exonic region (first two exons) of the hTERT gene. To better understand the mechanism involved and to identify a potentia...

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Bibliographic Details
Main Authors: Renaud, Stéphanie, Loukinov, Dmitri, Bosman, Fred T., Lobanenkov, Victor, Benhattar, Jean
Format: Artigo
Language:Inglês
Published: Oxford University Press 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301598/
https://ncbi.nlm.nih.gov/pubmed/16326864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki989
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