HIV-1 capsid protein forms spherical (immature-like) and tubular (mature-like) particles in vitro: structure switching by pH-induced conformational changes.

The viral genome and replicative enzymes of the human immunodeficiency virus are encased in a shell consisting of assembled mature capsid protein (CA). The core shell is a stable, effective protective barrier, but is also poised for dissolution on cue to allow transmission of the viral genome into i...

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Bibliographic Details
Main Authors: Ehrlich, L S, Liu, T, Scarlata, S, Chu, B, Carter, C A
Format: Artigo
Language:Inglês
Published: 2001
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301537/
https://ncbi.nlm.nih.gov/pubmed/11423440
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