Mouse mast cell secretory granules can function as intracellular ionic oscillators.

Fluorescent Ca2+ probes and digital photo-sectioning techniques were used to directly study the dynamics of Ca2+ in isolated mast cell granules of normal (CB/J) and beige (Bg(j)/Bg(j)) mice. The resting intraluminal free Ca2+ concentration ([Ca2+]L) is 25 +/- 4.2 microM (mean +/- SD, n = 68). Exposu...

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Autors principals: Quesada, I, Chin, W C, Steed, J, Campos-Bedolla, P, Verdugo, P
Format: Artigo
Idioma:Inglês
Publicat: 2001
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301405/
https://ncbi.nlm.nih.gov/pubmed/11325716
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