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The topology of lysine-containing amphipathic peptides in bilayers by circular dichroism, solid-state NMR, and molecular modeling.

In order to better understand the driving forces that determine the alignment of amphipathic helical polypeptides with respect to the surface of phospholipid bilayers, lysine-containing peptide sequences were designed, prepared by solid-phase chemical synthesis, and reconstituted into membranes. CD...

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Bibliographic Details
Main Authors: Vogt, B, Ducarme, P, Schinzel, S, Brasseur, R, Bechinger, B
Format: Artigo
Language:Inglês
Published: 2000
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301145/
https://ncbi.nlm.nih.gov/pubmed/11053137
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