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Structure, Topology and Tilt of Cell-Signaling Peptides Containing Nuclear Localization Sequences in Membrane Bilayers Determined by Solid-State NMR and Molecular Dynamics Simulation Studies

Cell-signaling peptides have been extensively used to transport functional molecules across the plasma membrane into living cells. These peptides consist of a hydrophobic sequence and a cationic nuclear localization sequence (NLS). It has been assumed that the hydrophobic region penetrates through t...

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Detalhes bibliográficos
Main Authors: Ramamoorthy, Ayyalusamy, Kandasamy, Senthil K., Lee, Dong-Kuk, Kidambi, Srikanth, Larson, Ronald G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527728/
https://ncbi.nlm.nih.gov/pubmed/17240980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi061895g
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