Chloride channels of glycine and GABA receptors with blockers: Monte Carlo minimization and structure-activity relationships.

GABA and glycine receptors (GlyRs) are pentameric ligand-gated ion channels that respond to the inhibitory neurotransmitters by opening a chloride-selective central pore lined with five M2 segments homologous to those of alpha(1) GlyR/ ARVG(2')LGIT(6')TVLTMTTQSSGSR. The activity of cyanotr...

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Hlavní autoři: Zhorov, B S, Bregestovski, P D
Médium: Artigo
Jazyk:Inglês
Vydáno: 2000
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300774/
https://ncbi.nlm.nih.gov/pubmed/10733960
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