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Comparison of Ca(2+) sparks produced independently by two ryanodine receptor isoforms (type 1 or type 3).

The molecular determinants of a Ca(2+) spark, those events that determine the sudden opening and closing of a small number of ryanodine receptor (RyR) channels limiting Ca(2+) release to a few milliseconds, are unknown. As a first step we investigated which of two RyR isoforms present in mammalian e...

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Autores principales: Conklin, M W, Ahern, C A, Vallejo, P, Sorrentino, V, Takeshima, H, Coronado, R
Formato: Artigo
Lenguaje:Inglês
Publicado: 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300773/
https://ncbi.nlm.nih.gov/pubmed/10733959
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