Conformation, independent of charge, in the R domain affects cystic fibrosis transmembrane conductance regulator channel openings.

The R domain of cystic fibrosis transmembrane conductance regulator (CFTR), when phosphorylated, undergoes conformational change, and the chloride channel opens. We investigated the contribution of R domain conformation, apart from the changes induced by phosphorylation, to channel opening, by testi...

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Detaylı Bibliyografya
Asıl Yazarlar: Xie, J, Zhao, J, Davis, P B, Ma, J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2000
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300730/
https://ncbi.nlm.nih.gov/pubmed/10692317
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