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Vectorial budding of vesicles by asymmetrical enzymatic formation of ceramide in giant liposomes.

Sphingomyelin is an abundant component of eukaryotic membranes. A specific enzyme, sphingomyelinase can convert this lipid to ceramide, a central second messenger in cellular signaling for apoptosis (programmed cell death), differentiation, and senescence. We used microinjection and either Hoffman m...

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Autors principals: Holopainen, J M, Angelova, M I, Kinnunen, P K
Format: Artigo
Idioma:Inglês
Publicat: 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300685/
https://ncbi.nlm.nih.gov/pubmed/10653795
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