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Effect of a concentrated "inert" macromolecular cosolute on the stability of a globular protein with respect to denaturation by heat and by chaotropes: a statistical-thermodynamic model.

An equilibrium statistical-thermodynamic model for the effect of volume exclusion arising from high concentrations of stable macromolecules upon the stability of a trace globular protein with respect to denaturation by heat and by chaotropes is presented. The stable cosolute and the native form of t...

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Bibliografische gegevens
Hoofdauteur: Minton, A P
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2000
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300621/
https://ncbi.nlm.nih.gov/pubmed/10620277
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