Nickel block of three cloned T-type calcium channels: low concentrations selectively block alpha1H.

Nickel has been proposed to be a selective blocker of low-voltage-activated, T-type calcium channels. However, studies on cloned high-voltage-activated Ca(2+) channels indicated that some subtypes, such as alpha1E, are also blocked by low micromolar concentrations of NiCl(2). There are considerable...

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Bibliographic Details
Main Authors: Lee, J H, Gomora, J C, Cribbs, L L, Perez-Reyes, E
Format: Artigo
Language:Inglês
Published: 1999
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300574/
https://ncbi.nlm.nih.gov/pubmed/10585925
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