Mg(2+) block unmasks Ca(2+)/Ba(2+) selectivity of alpha1G T-type calcium channels.

We have examined permeation by Ca(2+) and Ba(2+), and block by Mg(2+), using whole-cell recordings from alpha1G T-type calcium channels stably expressed in HEK 293 cells. Without Mg(o)(2+), inward currents were comparable with Ca(2+) and Ba(2+). Surprisingly, three other results indicate that alpha1...

Full description

Saved in:
Bibliographic Details
Main Authors: Serrano, J R, Dashti, S R, Perez-Reyes, E, Jones, S W
Format: Artigo
Language:Inglês
Published: 2000
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301182/
https://ncbi.nlm.nih.gov/pubmed/11106611
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items