An autoinhibitory peptide from the erythrocyte Ca-ATPase aggregates and inhibits both muscle Ca-ATPase isoforms.

We have studied the effects of C28R2, a basic peptide derived from the autoinhibitory domain of the plasma membrane Ca-ATPase, on enzyme activity, oligomeric state, and E1-E2 conformational equilibrium of the Ca-ATPase from skeletal and cardiac sarcoplasmic reticulum (SR). Time-resolved phosphoresce...

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Bibliografiske detaljer
Main Authors: Reddy, L G, Shi, Y, Kutchai, H, Filoteo, A G, Penniston, J T, Thomas, D D
Format: Artigo
Sprog:Inglês
Udgivet: 1999
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300275/
https://ncbi.nlm.nih.gov/pubmed/10354431
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