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PKQuest: capillary permeability limitation and plasma protein binding – application to human inulin, dicloxacillin and ceftriaxone pharmacokinetics
BACKGROUND: It is generally assumed that the tissue exchange of antibiotics is flow limited (complete equilibration between the capillary and the tissue water). This assumption may not be valid if there is a large amount of plasma protein binding because the effective capillary permeability depends...
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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BioMed Central
2002
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| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC130020/ https://ncbi.nlm.nih.gov/pubmed/12323078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6904-2-7 |
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