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What you should know about PR3-ANCA: Conformational requirements of proteinase 3 (PR3) for enzymatic activity and recognition by PR3-ANCA

The neutrophil azurophil granule constituent proteinase 3 (PR3) is the principal antigen for anti-neutrophil cytoplasmic antibodies (ANCA) in Wegener's granulomatosis. The conformation of the mature PR3 enzyme results from intracellular post-translational processing. The nascent molecule underg...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Specks, Ulrich
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2000
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC130016/
https://ncbi.nlm.nih.gov/pubmed/11094439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar99
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