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Exploration of the structural features defining the conduction properties of a synthetic ion channel.

The finite-difference Poisson-Boltzmann methodology was applied to a series of parallel, alpha-helical bundle models of the designed ion channel peptide Ac-(LSSLLSL)3-CONH2. This method is able to fully describe the current-voltage curves for this channel and quantitatively explains their cation sel...

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Detalhes bibliográficos
Main Authors: Dieckmann, G R, Lear, J D, Zhong, Q, Klein, M L, DeGrado, W F, Sharp, K A
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300068/
https://ncbi.nlm.nih.gov/pubmed/9929468
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