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Hydration structure of antithrombin conformers and water transfer during reactive loop insertion.

The serine protease inhibitor antithrombin undergoes extensive conformational changes during functional interaction with its target proteases. Changes include insertion of the reactive loop region into a beta-sheet structure in the protein core. We explore the possibility that these changes are link...

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Detalhes bibliográficos
Main Authors: Liang, J, McGee, M P
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1299733/
https://ncbi.nlm.nih.gov/pubmed/9675160
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