Perturbation of β1-Integrin Function in Involuting Mammary Gland Results in Premature Dedifferentiation of Secretory Epithelial Cells

To study the mechanism of β1-integrin function in vivo, we have generated transgenic mouse expressing a dominant negative mutant of β1-integrin under the control of mouse mammary tumor virus (MMTV) promoter (MMTV-β1-cyto). Mammary glands from MMTV-β1-cyto transgenic females present significant growt...

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Pubblicato in:	Mol Biol Cell
Autori principali:	Faraldo, Marisa M., Deugnier, Marie-Ange, Tlouzeau, Sylvie, Thiery, Jean Paul, Glukhova, Marina A.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Cell Biology 2002
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129963/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12388754/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E02-02-0086
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