Identification of a Chromogranin A Domain That Mediates Binding to Secretogranin III and Targeting to Secretory Granules in Pituitary Cells and Pancreatic β-Cells

Chromogranin A (CgA) is transported restrictedly to secretory granules in neuroendocrine cells. In addition to pH- and Ca(2+)-dependent aggregation, CgA is known to bind to a number of vesicle matrix proteins. Because the binding-prone property of CgA with secretory proteins may be essential for its...

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Pubblicato in:	Mol Biol Cell
Autori principali:	Hosaka, Masahiro, Watanabe, Tsuyoshi, Sakai, Yuko, Uchiyama, Yasuo, Takeuchi, Toshiyuki
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Cell Biology 2002
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129953/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12388744/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.02-03-0040
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