Woodchuck post-transcriptional element induces nuclear export of myotonic dystrophy 3′ untranslated region transcripts

The woodchuck post-transcriptional regulatory element (WPRE) can naturally accumulate hepatitis transcripts in the cytoplasm, and has been recently exploited as an enhancer of transgene expression. The retention of mutant myotonic dystrophy protein kinase (DMPK) transcripts in the nucleus of myotoni...

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Bibliographic Details
Main Authors: Mastroyiannopoulos, Nikolaos P, Feldman, Mariana L, Uney, James B, Mahadevan, Mani S, Phylactou, Leonidas A
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Scientific Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1299300/
https://ncbi.nlm.nih.gov/pubmed/15832171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400390
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