Characterization of the interactions between mammalian PAZ PIWI domain proteins and Dicer

PAZ PIWI domain (PPD) proteins, together with the RNA cleavage products of Dicer, form ribonucleoprotein complexes called RNA-induced silencing complexes (RISCs). RISCs mediate gene silencing through targeted messenger RNA cleavage and translational suppression. The PAZ domains of PPD and Dicer prot...

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Bibliografiske detaljer
Main Authors: Tahbaz, Nasser, Kolb, Fabrice A, Zhang, Haidi, Jaronczyk, Katarzyna, Filipowicz, Witold, Hobman, Tom C
Format: Artigo
Sprog:Inglês
Udgivet: 2004
Fag:
Scientific Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1298981/
https://ncbi.nlm.nih.gov/pubmed/14749716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400070
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