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Yeast N-glycanase distinguishes between native and non-native glycoproteins

N-glycanase from Saccharomyces cerevisiae (Png1) preferentially removes N-glycans from misfolded proteins. The ability of Png1 to distinguish between folded and misfolded glycoproteins is reminiscent of substrate recognition by UDP-glucose glycoprotein glucosyl transferase, an enzyme that possesses...

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Detalhes bibliográficos
Main Authors: Hirsch, Christian, Misaghi, Shahram, Blom, Daniël, Pacold, Michael E, Ploegh, Hidde L
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1298977/
https://ncbi.nlm.nih.gov/pubmed/14726951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400066
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