Amino acid deletions are introduced into the V2 region of gp120 during independent pathogenic simian immunodeficiency virus/HIV chimeric virus (SHIV) infections of rhesus monkeys generating variants that are macrophage tropic

Highly pathogenic simian immunodeficiency virus/HIV chimeric viruses (SHIVs) cause extremely rapid, irreversible, and systemic depletions of CD4(+) T lymphocytes in inoculated rhesus monkeys. In the absence of this T cell subset, virus production can be sustained for several months by tissue macroph...

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Autores principales: Imamichi, Hiromi, Igarashi, Tatsuhiko, Imamichi, Tomozumi, Donau, Olivia K., Endo, Yasuyuki, Nishimura, Yoshiaki, Willey, Ronald L., Suffredini, Anthony F., Lane, H. Clifford, Martin, Malcolm A.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2002
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC129780/
https://ncbi.nlm.nih.gov/pubmed/12370415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212511599
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