Raloxifene reduces urokinase-type plasminogen activator-dependent proliferation of synoviocytes from patients with rheumatoid arthritis

Extracellular fibrinolysis, controlled by the membrane-bound fibrinolytic system, is involved in cartilage damage and rheumatoid arthritis (RA) synovitis. Estrogen status and metabolism seem to be impaired in RA, and synoviocytes show receptors for estrogens. Our aims in this study were to evaluate...

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Detalhes bibliográficos
Main Authors: Guiducci, S, Del Rosso, A, Cinelli, M, Perfetto, F, Livi, R, Rossi, A, Gabrielli, A, Giacomelli, R, Iori, N, Fibbi, G, Del Rosso, M, Cerinic, M Matucci
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1297569/
https://ncbi.nlm.nih.gov/pubmed/16277677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1815
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