Rheumatoid arthritis seropositive for the rheumatoid factor is linked to the protein tyrosine phosphatase nonreceptor 22-620W allele

The protein tyrosine phosphatase nonreceptor type 22 (PTPN22) gene encodes for lymphoid tyrosine phosphatase LYP, involved in the negative regulation of early T-cell activation. An association has recently been reported between the PTPN22-620W functional allele and rheumatoid factor-positive (RF(+))...

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Autori principali: Dieudé, Philippe, Garnier, Sophie, Michou, Laëtitia, Petit-Teixeira, Elisabeth, Glikmans, Elodie, Pierlot, Céline, Lasbleiz, Sandra, Bardin, Thomas, Prum, Bernard, Cornélis, François
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2005
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1297567/
https://ncbi.nlm.nih.gov/pubmed/16277672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1812
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