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Is ghrelin a signal for the development of metabolic systems?

Ghrelin, produced in the stomach, acts on growth hormone secretagogue receptors (GHSRs) in hypothalamic neurons to potently increase food intake. However, male mice with deletions of ghrelin (Ghrl(–/–) mice) or GHSR (Ghsr(–/–) mice) display normal growth and regulation of food intake. Furthermore, a...

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Autori principali: Grove, Kevin L., Cowley, Michael A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1297272/
https://ncbi.nlm.nih.gov/pubmed/16322785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27211
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