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Is ghrelin a signal for the development of metabolic systems?
Ghrelin, produced in the stomach, acts on growth hormone secretagogue receptors (GHSRs) in hypothalamic neurons to potently increase food intake. However, male mice with deletions of ghrelin (Ghrl(–/–) mice) or GHSR (Ghsr(–/–) mice) display normal growth and regulation of food intake. Furthermore, a...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2005
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1297272/ https://ncbi.nlm.nih.gov/pubmed/16322785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27211 |
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