Regulation of glucagon secretion by glucose transporter type 2 (glut2) and astrocyte-dependent glucose sensors

Ripglut1;glut2(–/–) mice have no endogenous glucose transporter type 2 (glut2) gene expression but rescue glucose-regulated insulin secretion. Control of glucagon plasma levels is, however, abnormal, with fed hyperglucagonemia and insensitivity to physiological hypo- or hyperglycemia, indicating tha...

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Detalhes bibliográficos
Main Authors: Marty, Nell, Dallaporta, Michel, Foretz, Marc, Emery, Martine, Tarussio, David, Bady, Isabelle, Binnert, Christophe, Beermann, Friedrich, Thorens, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1297256/
https://ncbi.nlm.nih.gov/pubmed/16322792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26309
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