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Helix–hairpin–helix motifs confer salt resistance and processivity on chimeric DNA polymerases

Helix–hairpin–helix (HhH) is a widespread motif involved in sequence-nonspecific DNA binding. The majority of HhH motifs function as DNA-binding modules with typical occurrence of one HhH motif or one or two (HhH)(2) domains in proteins. We recently identified 24 HhH motifs in DNA topoisomerase V (T...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Pavlov, Andrey R., Belova, Galina I., Kozyavkin, Sergei A., Slesarev, Alexei I.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129704/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12368475/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.202127199
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